MUbio

Lamin A and C Monoclonal Antibody (131C3), FITC

Name: Lamin A and C Monoclonal Antibody (131C3), FITC
Brand: MUbio
SKU: MUB1102L1

查看其他32个Lamin A/C抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

产品信息

MUB1102L1

应用

建议稀释比

已发表文章

免疫组化（冰冻） (IHC (F))

Assay-dependent

免疫细胞化学 (ICC/IF)

Assay-dependent

流式细胞分析 (Flow)

Assay-dependent

产品规格

种属反应

Bovine, Dog, Hamster, Human, Mouse, Sheep, Rat

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

131C3

抗原

Lamin A and C

偶联物

FITC FITC FITC

激发/发射光谱

498/517 nm 查看光谱

形式

Liquid

浓度

0.1 mL/Test

纯化类型

Protein A/G

保存液

PBS with 0.1% BSA

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

131C3 reacts with an epitope located between residues 319-566 in lamin A and C.

The antibody may be stored at 4°C. For prolonged storage prepare appropriate aliquots and store at or below -20°C. Prior to use, an aliquot is thawed slowly in the dark at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at 4°C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance or the concentration of the product.

靶标信息

Lamins are a class of intermediate filament proteins that form a matrix on the inner surface of the nuclear envelope. These proteins are found in many different cell types in three different forms (A, B, and C). Lamins A and C are alternatively spliced versions of the LMNA gene. The LMNA gene has been linked to many disorders of the muscular system, nervous system, and the fat distributions systems including: Emery-Dreifuss muscular dystrophy, Dunnigan-type familial partial lipodystrophy (FPLD), limb-girdle muscular dystrophy (LGMD1B), dilated cardiomyopathy (CMD1A), axonal neuropathy (Charcot-Marie-Tooth disease; CMT2B1), and mandibuloacral dysplasia (MAD).

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: 70 kDa lamin; lamin A; Lamin A+C mutant; lamin a-c; lamin A/C; lamin A/C-like 1; Lamin AC; lamin C; lamin C2; lamin-A/C; mutant 453W; Mutant lamin A/C; Prelamin-A/C; progerin mutant; renal carcinoma antigen NY-REN-32; RP11-54H19.1; unnamed protein product

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基因别名: CDCD1; CDDC; CMD1A; CMT2B1; Dhe; EMD2; FPL; FPLD; FPLD2; HGPS; I79_009616; IDC; Lamin-A/C; LDP1; LFP; LGMD1B; LMN1; LMNA; LMNC; LMNL1; PRO1

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UniProt ID: (Human) P02545, (Mouse) P48678