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QED Bioscience
Lipoteichoic Acid Monoclonal Antibody (15711)
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产品信息
15711-500UG
产品规格
种属反应
Bacteria
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
15711
抗原
Staphylococcus epidermidis, Hay strain (ATCC #55133).
偶联物
形式
Liquid
浓度
0.5-1.0 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Lipoteichoic acid (LTA) is a glycerol phosphate surface polymer component of the envelope of Gram-positive bacteria. LTA is anchored via its glycolipids to the membrane and carries a polysaccharide chain extending into the peptidoglycan layer of the cell wall. LTA is released spontaneously into the culture medium during growth of gram-positive bacteria. LTA functions as an immune activator with characteristics very similar to lipopolysaccharide (LPS) from Gram-negative bacteria. LTA binds to CD14 and triggers activation predominantly via Toll-like receptor 2. Although LTA is internalized and traffics to the Golgi, the cellular activation in response to LTA occurs at the cell surface.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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