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Invitrogen
Lipoteichoic Acid (Pagibaximab Biosimilar) Recombinant Human Monoclonal Antibody
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Lipoteichoic Acid (Pagibaximab Biosimilar) Antibody (MA5-41849) in SDS-PAGE
SDS-PAGE analysis of the recombinant Staphylococcus epidermidis lipoteichoic acid protein expressed in CHO cells using a Lipoteichoic Acid (Pagibaximab Biosimilar) monoclonal antibody (Product # MA5-41849). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
产品信息
MA5-41849
产品规格
种属反应
Bacteria
宿主/亚型
Human
/ IgG1, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Staphylococcus epidermidis lipoteichoic acid
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
MA5-41849 is a chimeric antibody. The variable regions from one species have been grafted to the backbone of the other species.
靶标信息
Lipoteichoic acid (LTA) is a glycerol phosphate surface polymer component of the envelope of Gram-positive bacteria. LTA is anchored via its glycolipids to the membrane and carries a polysaccharide chain extending into the peptidoglycan layer of the cell wall. LTA is released spontaneously into the culture medium during growth of gram-positive bacteria. LTA functions as an immune activator with characteristics very similar to lipopolysaccharide (LPS) from Gram-negative bacteria. LTA binds to CD14 and triggers activation predominantly via Toll-like receptor 2. Although LTA is internalized and traffics to the Golgi, the cellular activation in response to LTA occurs at the cell surface.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: LTA
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