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Positive control: Transfected HEK-293 cells.
This antibody can be used for Western blotting (10-15 µg/mL). Optimal concentration should be evaluated by serial dilutions. NOTE: Boiling LPP2 with sample buffer will aggregate the protein. Lysates should be prepared by mixing cells with lysis buffer (possibly with extra detergent) to solubilize the protein before adding sample buffer and lysate SHOULD NOT be boiled/heated.
Phosphatidic acid phosphatase type 2 (PAP2) was originally identified as a plasma membrane enzyme that catalyses the dephosphorylation of the putative second messenger, phosphatidic acid (PA) to diacylglycerol (DG). Subsequently, multiple isoforms of PAP2 were cloned [2-5]. It was found that these enzymes dephosphorylate a number of lipid phosphates in vitro other than PA, including the potent bioactive lipids, lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P). Therefore, they have been renamed lipid phosphate phosphatases (LPPs). Currently, there are four members of this family called LPP1, LPP1a, LPP2 and LPP3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Lipid phosphate phosphohydrolase 2; LPR3; PAP-2c; PAP2-G; PAP2-gamma; PAP2c; Phosphatidate phosphohydrolase type 2c; Phosphatidic acid phosphatase 2c; phosphatidic acid phosphatase type 2C; phosphatidic acid phosphohydrolase type 2c; Phospholipid phosphatase 2; PRG-2; PRG2; type-2 phosphatidic acid phosphatase-gamma
基因别名: LPP2; PAP-2c; PAP2-g; PLPP2; PPAP2C
UniProt ID: (Human) O43688
Entrez Gene ID: (Human) 8612