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Invitrogen
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Immunogen sequence: HGYASVLPFDG DFAREKTKAA GLVRKAPNNR SSHNEL
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
This gene is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。