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Proteintech
MAG Polyclonal Antibody
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产品信息
14386-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MAG Fusion Protein Ag5845 (199-516 aa encoded by BC053347)
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: VSLLHFVPT REANGHRLGC QASFPNTTLQ FEGYASMDVK YPPVIVEMNS SVEAIEGSHV SLLCGADSNP PPLLTWMRDG TVLREAVAES LLLELEEVTP AEDGVYACLA ENAYGQDNRT VGLSVMYAPW KPTVNGTMVA VEGETVSILC STQSNPDPIL TIFKEKQILS TVIYESELQL ELPAVSPEDD GEYWCVAENQ YGQRATAFNL SVEFAPVLLL ESHCAAARDT VQCLCVVKSN PEPSVAFELP SRNVTVNESE REFVYSERSG LVLTSILTLR GQAQAPPRVI CTARNLYGAK SLELPFQGAH RLMWAKIGP (199-516 aa encoded by BC053347)
靶标信息
The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 1B236; Brain neuron cytoplasmic protein 3; Myelin-associated glycoprotein; S-MAG (C-term.); sialic acid binding Ig-like lectin 4A; Sialic acid-binding Ig-like lectin 4a; sialic acid-binding immunoglobulin-like lectin 4A; Siglec-4a
基因别名: GMA; MAG; S-MAG; SIGLEC-4A; SIGLEC4A; SPG75
UniProt ID: (Human) P20916, (Rat) P07722, (Mouse) P20917
Entrez Gene ID: (Human) 4099, (Rat) 29409, (Mouse) 17136
cell adhesion
positive regulation of myelination
positive regulation of astrocyte differentiation
negative regulation of axonogenesis
leukocyte migration
cellular response to mechanical stimulus
nervous system development
negative regulation of neuron projection development
substantia nigra development
negative regulation of neuron differentiation
