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Proteintech
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Immunogen sequence: MPRGQKSKL RAREKRHQAR CENQDLGATQ ATVAEGESPS SAYLLFGDRP QNLPAAETPS IPEALQGAPS TTNAIAPVSC SSNEGASSQD EKSLGSSREA EGWKEDPLNK KVVSLVHFLL QKYETKEPIT KGDMIKFVIR KDKCHFNEIL KRASEHMELA LGVDLKEVDP IRHYYAFFSK LDLTYDETTS DEEKIPKTGL LMIALGVIFL NGNRAPEEAV WEIMNMMGVY ADRKHFLYGD PRKVMTKDLV QLKYLEYQQV PNSDPPRYEF LWGPRAHAET SKMKVLEFVA KIHDTVPSAF PSCYEEALRD EEQRTQARAA ARAHTAAMAN ARSRTTSSSF SHAK (1-343 aa encoded by BC029525)
The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MAGBI; MAGE-B18 antigen; melanoma antigen family B, 18; melanoma antigen family B18; Melanoma-associated antigen B18
基因别名: MAGEB18
UniProt ID: (Human) Q96M61
Entrez Gene ID: (Human) 286514