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Proteintech
MANEA Polyclonal Antibody
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产品信息
21296-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MANEA Fusion Protein Ag15847 (29-109 aa encoded by BC146671)
偶联物
形式
Liquid
浓度
0.25 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LRPNTATFG APFGLDLLPE LHQRTIHLGK NFDFQKSDRI NSETNTKNLK SVEITMKPSK ASELNLDELP PLNNYLHVFY YS (29-109 aa encoded by BC146671)
靶标信息
N-glycosylation of proteins is initiated in the endoplasmic reticulum (ER) by the transfer of the preassembled oligosaccharide glucose-3-mannose-9-N-acetylglucosamine-2 from dolichyl pyrophosphate to acceptor sites on the target protein by an oligosaccharyltransferase complex. This core oligosaccharide is sequentially processed by several ER glycosidases and by an endomannosidase (E.C. 3.2.1.130), such as MANEA, in the Golgi. MANEA catalyzes the release of mono-, di-, and triglucosylmannose oligosaccharides by cleaving the alpha-1,2-mannosidic bond that links them to high-mannose glycans (Hamilton et al., 2005).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: alpha 1,2-endomannosidase; Endo-alpha mannosidase; endomannosidase; Glycoprotein endo-alpha-1,2-mannosidase; Mandaselin; mannosidase, endo-alpha; mEndo
基因别名: 4932703L02Rik; ENDO; hEndo; MANEA
UniProt ID: (Human) Q5SRI9, (Mouse) Q6NXH2
Entrez Gene ID: (Human) 79694, (Mouse) 242362
