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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. In response to cellular stress and upon mitochondria fission, binds C-18 ceramides and anchors autophagolysosomes to outer mitochondrial membranes to eliminate damaged mitochondria. While LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ATG8G; MAP1A/MAP1B LC3 B-like; MAP1LC3B2; Microtubule associated protein 1 light chain 3 beta 2; Microtubule associated proteins 1A/1B light chain 3B like protein; Microtubule-associated protein 1 light chain 3 beta 2; Microtubule-associated proteins 1A/1B light chain 3 beta 2; Microtubule-associated proteins 1A/1B light chain 3B-like; MP3B2_HUMAN
基因别名: MAP1LC3B2
Entrez Gene ID: (Human) 643246