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Invitrogen
MAP4 Polyclonal Antibody
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MAP4 Antibody (PA5-96473) in IHC (P)
Immunohistochemistry analysis of MAP4 in paraffin-embedded mouse kidney. Samples were incubated with MAP4 Polyclonal antibody (Product # PA5-96473) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
产品信息
PA5-96473
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 942-1152 of human MAP4 (NP_0023662)
偶联物
形式
Liquid
浓度
2.09 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: TENIKHQPGG GRAKVEKKTE AAATTRKPES NAVTKTAGPI ASAQKQPAGK VQIVSKKVSY SHIQSKCGSK DNIKHVPGGG NVQIQNKKVD ISKVSSKCGS KANIKHKPGG GDVKIESQKL NFKEKAQAKV GSLDNVGHLP AGGAVKTEGG GSEAPLCPGP PAGEEPAISE AAPEAGAPTS ASGLNGHPTL SGGGDQREAQ TLDSQIQETS I; Positive Samples: U-87MG; Cellular Location: Cytoplasm, cytoskeleton
靶标信息
The protein encoded by this gene is a major non-neuronal microtubule-associated protein. This protein contains a domain similar to the microtubule-binding domains of neuronal microtubule-associated protein (MAP2) and microtubule-associated protein tau (MAPT/TAU). This protein promotes microtubule assembly, and has been shown to counteract destabilization of interphase microtubule catastrophe promotion. Cyclin B was found to interact with this protein, which targets cell division cycle 2 (CDC2) kinase to microtubules. The phosphorylation of this protein affects microtubule properties and cell cycle progression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MAP 4; MAP-4; Microtubule-associated protein 4
基因别名: AA407148; MAP-4; MAP4; Mtap-4; Mtap4
UniProt ID: (Human) P27816, (Mouse) P27546
Entrez Gene ID: (Human) 4134, (Mouse) 17758
