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Invitrogen
MATN4 Polyclonal Antibody
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MATN4 Antibody (PA5-96206) in WB
Western blot analysis of MATN4 in extracts of various cell lines. Samples were incubated with MATN4 Polyclonal antibody (Product # PA5-96206) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-96206
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 221-540 of human MATN4 (NP_0850801)
偶联物
形式
Liquid
浓度
1.04 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: FGNHSCQHEC VSTPGGPRCH CREGHDLQPD GRSCQVRDLC NGVDHGCEFQ CVSEGLSYRC LCPEGRQLQA DGKSCNRCRE GHVDLVLLVD GSKSVRPQNF ELVKRFVNQI VDFLDVSPEG TRVGLVQFSS RVRTEFPLGR YGTAAEVKQA VLAVEYMERG TMTGLALRHM VEHSFSEAQG ARPRALNVPR VGLVFTDGRS QDDISVWAAR AKEEGIVMYA VGVGKAVEAE LREIASEPAE LHVSYAPDFG TMTHLLENLR GSICPEEGIS AGTELRSPCE CESLVEFQGR TLGALESLTL NLAQLTARLE DLENQLANQK; Positive Samples: HepG2, NCI-H460, Mouse heart, Rat kidney
靶标信息
Matrilin (MATNs) are a family of non-collagenous extracellular matrix proteins consisting of four known members that have been proposed to play key roles in the formation of both collagen-dependent and collagen-independent filamentous networks. Members of the matrilin family all share a structure made up of von Willebrand factor A domains, epidermal growth factor-like domains and a coiled coil alpha-helical module. MATN1 and MATN3 are expressed mainly in cartilage, while MATN2 and MATN4 occur in a wide variety of extracellular matrices such as embryonic kidney, lung, bone, cartilage and nervous system. The matrilin genes are strictly and differently regulated and their expression may serve as markers for cellular differentiation. MATN4 could serve as an odontoblast differentiation marker, e.g. in odontoblast stem cell research.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HE6WCR54; MAT-4; Matrilin-4
基因别名: MATN4; matrilin-4
UniProt ID: (Human) O95460, (Mouse) O89029
Entrez Gene ID: (Human) 8785, (Rat) 296358, (Mouse) 17183
