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Invitrogen
MAdCAM1 Monoclonal Antibody (314G8)
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产品信息
MA1-81757
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
314G8
抗原
Recombinant protein.
偶联物
Unconjugated
Unconjugated
Unconjugated
保存条件
4°C
产品详细信息
MA1-81757 detects MAdCAM-1 in human sample types.
MA1-81757 has been successfully used in ELISA,Western blot, Flow cytometry and Immunohistochemistry (paraffin) applications.
The immunogen used to produce MA1-81757 is from recombinant soluble MAdCAM-1-fc fusion protein.
Mouse anti Human MAdCAM-1 antibody, clone 314G8 recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1) a 60kD cell surface protein that is involved in lymphocyte trafficking.
靶标信息
The protein encoded by this gene is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4 (alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven alternatively spliced transcripts encoding different protein isoforms have been found for this gene, but the full-length nature of some variants has not been determined.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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