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Invitrogen
MBL2 Monoclonal Antibody (3B6), Biotin
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产品信息
HYB 131-01B-005
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
3B6
抗原
MBL purified from human donor plasma
偶联物
形式
Liquid
浓度
0.92 mg/mL
保存条件
4°C, store in dark, DO NOT FREEZE!
运输条件
Wet ice
RRID
产品详细信息
HYB 131-01B-005 is specific for MBL from human serum or plasma.
HYB 131-01B-005 has been successfully used in ELISA. Used as detection antibody in sandwich ELISA with a mannan or HYB 131-01B-005 coat, HYB 131-01B-005 is selective for normally oligomerized MBL.
The HYB 131-01B-005 immunogen is MBL purified from human donor plasma.
Epitope specificity differs from that of HYB 131-10-02 and HYB 131-11-02. Epitope is near the carbohydrate-binding site.
NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
靶标信息
MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. It also binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 may bind DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
