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Proteintech
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SQLLKFVEK CSPIGVYTSG KGSSAAGLTA SVMRDPSSRN FIMEGGAMVL ADGGVVCIDE FDKMREDDRV AIHEAMEQQT ISIAKAGITT TLNSRCSVLA AANSVFGRWD ETKGEDNIDF MPTILSRFDM IFIVKDEHNE ERDVMLAKHV ITLHVSALTQ TQAVEGEIDL AKLKKFIAYC RVKCGPRLSA EAAEKLKNRY IIMRSGARQH ERDSDRRSSI PITVRQLEAI VRIAEALSKM KLQPFATEAD VEEALRLFQV STLDAALSGT LSGVEGFTSQ EDQEMLSRIE KQLKRRFAIG SQVSEHSIIK DFTKQKYPEH AIHKVLQLML RRGEIQHRMQ RKVLYRLK (388-735 aa encoded by BC000142)
The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CDC46 homolog; MCM5; MCM5 minichromosome maintenance deficient 5, cell division cycle 46; MGC5315; mini chromosome maintenance deficient 5; minichromosome maintenance deficient 5 (cell division cycle 46); minichromosome maintenance deficient 5, cell division cycle 46; unnamed protein product
基因别名: CDC46; Mcmd5; MGORS8; P1-CDC46
UniProt ID: (Human) P33992, (Mouse) P49718
Entrez Gene ID: (Human) 4174, (Mouse) 17218, (Rat) 291885