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OriGene
MDK Monoclonal Antibody (OTI8C6), TrueMAB™
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MDK Antibody (CF807775) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY MDK (RC221818, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-MDK. (1:2. Positive lysates LY425316 (100 µg) and LC425316 (20 µg) can be purchased separately from OriGene.
产品信息
CF807775
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OTI8C6
抗原
Human recombinant protein fragment corresponding to amino acids 21-143 of human MDK produced in E.coli.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
Midkine is a retinoic acid-responsive, heparin-binding growth factor expressed in various cell types during embryogenesis. It promotes angiogenesis, cell growth, and cell migration. Midkine is also expressed in several carcinomas, suggesting that it may play a role in tumorigenesis, perhaps through its effects on angiogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Amphiregulin-associated protein; ARAP; FLJ27379; Midgestation and kidney protein; Midkine; MK; Neurite outgrowth-promoting factor 2; Neurite outgrowth-promoting protein; retinoic acid inducible factor
基因别名: ARAP; MDK; MK; MK1; NEGF2
UniProt ID: (Human) P21741
Entrez Gene ID: (Human) 4192
behavioral fear response
signal transduction
Notch signaling pathway
nervous system development
short-term memory
response to wounding
cell migration
dentate gyrus development
cerebellar granular layer development
cerebral cortex development
cell differentiation
adrenal gland development
defecation
response to drug
negative regulation of neuron apoptotic process
positive regulation of transcription, DNA-templated
regulation of behavior
response to glucocorticoid
positive regulation of cell division
