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Invitrogen
MEG2 Monoclonal Antibody (291835)
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MEG2 Antibody (MA5-23997) in WB
Western blot analysis of MEG2 in Raji human Burkitts lymphoma cell line, TS1 mouse helper T cell line, CTLL‚2 mouse cytotoxic T cell line, and Nb2‚11 rat lymphoma cell line. Samples were incubated in MEG2 monoclonal antibody (Product # MA5-23997) using a dilution of 1 µg/mL followed by a HRP-conjugated Anti-Mouse IgG secondary antibody. A specific band was detected for PTP-MEG2 at approximately 68 kDa (as indicated). This experiment was conducted under reducing conditions.
产品信息
MA5-23997
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
291835
抗原
E. coli-derived recombinant human PTP-MEG2 Glu2-Gln593
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
MEG2 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain that shares a significant similarity with yeast SEC14, which is a protein that has phosphatidylinositol transfer activity and is required for protein secretion through the Golgi complex in yeast. This PTP was found to be activated by polyphosphoinositide, and is thought to be involved in signaling events regulating phagocytosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: meg-2; Protein-tyrosine phosphatase MEG2; Protein-tyrosine phosphatase, non-receptor type 9 (Protein-tyrosine phosphatase MEG2) (PTPase-MEG2); PTPase MEG2; PTPase-MEG2; Tyrosine-protein phosphatase non-receptor type 9
基因别名: MEG2; PTPMEG2; PTPN9
UniProt ID: (Human) P43378, (Rat) Q641Z2, (Mouse) O35239
Entrez Gene ID: (Human) 5780, (Rat) 266611, (Mouse) 56294
