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Invitrogen
MEIS2 Polyclonal Antibody
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MEIS2 Antibody (PA5-97053) in WB
Western blot analysis of MEIS2 in extracts of various cell lines. Samples were incubated with MEIS2 Polyclonal antibody (Product # PA5-97053) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-97053
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 351-470 of human MEIS2 (NP_7337761)
偶联物
形式
Liquid
浓度
2.42 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: AYSPEGQPMG SFVLDGQQHM GIRPAGLQSM PGDYVSQGGP MGMSMAQPSY TPPQMTPHPT QLRHGPPMHS YLPSHPHHPA MMMHGGPPTH PGMTMSAQSP TMLNSVDPNV GGQVMDIHAQ; Positive Samples: Mouse kidney, Mouse heart, Rat kidney; Cellular Location: Cytoplasm, Nucleus, perinuclear region
靶标信息
This gene encodes a homeobox protein belonging to the TALE family of homeodomain-containing proteins. TALE homeobox proteins are highly conserved transcription regulators, and several members have been shown to be essential contributors to developmental programs. Multiple transcript variants encoding distinct isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 2; Homeobox protein Meis2; Meis1, myeloid ecotropic viral integration site 1 homolog 2; Meis1-related protein 1; Meis2 homeobox; MGC2820; myeloid ecotropic viral integration site-related gene 1; OTTHUMP00000160209
基因别名: A430109D20Rik; Meis2; Mrg1; Stra10
UniProt ID: (Mouse) P97367
Entrez Gene ID: (Mouse) 17536, (Rat) 311311
RNA polymerase II core promoter proximal region sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription cofactor activity
transcription factor binding
sequence-specific DNA binding
molecular_function
homeodomain transcription factor
eye development
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
multicellular organism development
negative regulation of myeloid cell differentiation
positive regulation of transcription from RNA polymerase II promoter
regulation of nucleic acid-templated transcription
response to mechanical stimulus
pancreas development
response to growth factor
