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Proteintech
MEMO1 Polyclonal Antibody
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产品信息
14604-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MEMO1 Fusion Protein Ag6151 (1-297 aa encoded by BC070046)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MSNRVVCRE ASHAGSWYTA SGPHLNAQLE GWLSQVQSTK RPARAIIAPH AGYTYCGSCA AHAYKQVDPS ITRRIFILGP SHHVPLSRCA LSSVDIYRTP LYDLRIDQKI YGELWKTGMF ERMSLQTDED EHSIEMHLPY TAKAMESHKD EFTIIPVLVG ALSESKEQEF GKLFSKYLAD PSNLFVVSSD FCHWGQRFRY SYYDESQGEI YRSIEHLDKM GMSIIEQLDP VSFSNYLKKY HNTICGRHPI GVLLNAITEL QKNGMNMSFS FLNYAQSSQC RNWQDSSVSY AAGALTVH (1-297 aa encoded by BC070046)
靶标信息
May control cell migration by relaying extracellular chemotactic signals to the microtubule cytoskeleton. Mediator of ERBB2 signaling. The MEMO1-RHOA-DIAPH1 signaling pathway plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. It controls the localization of APC and CLASP2 to the cell membrane, via the regulation of GSK3B activity. In turn, membrane-bound APC allows the localization of the MACF1 to the cell membrane, which is required for microtubule capture and stabilization. Is required for breast carcinoma cell migration.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C21orf19-like protein; HCV NS5A-transactivated protein 7; Hepatitis C virus NS5A-transactivated protein 7; Mediator of cell motility 1; Mediator of ErbB2-driven cell motility 1; Memo-1; protein memo; Protein MEMO1
基因别名: 0610016J10Rik; C2orf4; CGI-27; D930048L02Rik; MEMO; MEMO1; NS5ATP7; RGD1309929
UniProt ID: (Human) Q9Y316, (Mouse) Q91VH6, (Rat) Q4QQR9
Entrez Gene ID: (Human) 51072, (Mouse) 76890, (Rat) 298787
