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Antibodies Inc
MFF Monoclonal Antibody (N382/14)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
75-366
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
N382/14
抗原
Fusion protein amino acids 1-173 (cytoplasmic N-terminal exons 1, 2, 3 and 4) and 272-322 (cytoplasmic N-terminal exons 8 and most of 9) of mostly human MFF (also known as Mitochondrial fission factor, C2orf33, AD030, AD033 and GL004, accession number Q9GZY8).
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4
内含物
0.065% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Dry ice (international)
产品详细信息
For maximum recovery of product, centrifuge the vial prior to removing the cap.
Sequence of this protein is as follows: MSKRTSSDTP LGRVSGAAFP SPTASEMAEI SRIQYEMEYT EGISQRMRVP EKLKVAPPNA DLEQGFQEGV PNASVIMQVP ERIVVAGNNE DVSFSRPADL DLIQSTPFKP LALKTPPRVL TLSERPLDFL DLERPPVTPQ NEEIRAVGRL KRERSMSENA VRQNGQLVRN DSV
YGISNIEATI EGTSDDMTVV DAASLRRQII KLNRRLQLLE EENKERAKRE M
Human: 96% identity (167/173 amino acids identical) and 94% identity (48/51 amino acids identical); Rat: 95% identity (141/147 amino acids identical) and 92% identity (47/51 amino acids identical); Mouse: 93% identity (138/147 amino acids identical) and 84% identity (43/51 amino acids identical).
靶标信息
Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface. May be involved in regulation of synaptic vesicle membrane dynamics by recruitment of DNM1L to clathrin-containing vesicles. [Uniprot]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: unnamed protein product
基因别名: 5230400G24Rik; C2orf33; EMPF2; GL004; RGD1310230
UniProt ID: (Human) Q9GZY8, (Mouse) Q6PCP5, (Rat) Q4KM98
Entrez Gene ID: (Human) 56947, (Mouse) 75734, (Rat) 301563
mitochondrial fission
mitochondrion organization
positive regulation of cardiac muscle cell apoptotic process
peroxisome fission
protein localization to mitochondrion
positive regulation of mitochondrial fission
positive regulation of synaptic vesicle endocytosis
cellular response to hydrogen peroxide
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