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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive Control: A549 cell lysate, A431 cell lysate, HeLa cell lysate, MCF7 cell lysate, SK-Br-3 cell lysate, BT-20 cell lysate.
Tissue Specificity: Low tissue specificity.
Subcellular Location: Membrane, Secreted, Cytoplasmic vesicle, secretory vesicle, acrosome membrane.
Sequence Similarities: No Cross with Mouse/Rat.
Predicted band size: 43 kDa.
This gene encodes a preproprotein that is proteolytically processed to form multiple protein products. The major encoded protein product, lactadherin, is a membrane glycoprotein that promotes phagocytosis of apoptotic cells. This protein has also been implicated in wound healing, autoimmune disease, and cancer. Lactadherin can be further processed to form a smaller cleavage product, medin, which comprises the major protein component of aortic medial amyloid (AMA). Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Breast epithelial antigen BA46; HMFG; Lactadherin; MFG-E8; MFGM; milk fat globule membrane; milk fat globule membrane protein; Milk fat globule-EGF factor 8; SED1
基因别名: MFGE8
Entrez Gene ID: (Human) 4240