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Invitrogen
MIB2 Polyclonal Antibody
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MIB2 Antibody (PA5-119285) in IHC (P)
Immunohistochemistry analysis of MIB2 in paraffin-embedded Mouse Stomach tissue. Samples were incubated with polyclonal antibody (Product # PA5-119285) at a dilution of 10 µg/mL, followed by HRP-Linked Caprine Anti-Rabbit IgG using a dilution of 2 µg/mL.
产品信息
PA5-119285
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein Mindbomb Homolog 2. The antigen corresponds to amino acid range 546-784 of the target protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography, Protein A
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Dyslike; Dystrophin-like protein; E3 ubiquitin-protein ligase MIB2; EC 6.3.2.13; FLJ20648; FLJ41406; Mind bomb homolog 2; Mind bomb-2; RING-type E3 ubiquitin transferase MIB2; Skeletrophin; zinc finger, ZZ type with ankyrin repeat domain 1
基因别名: 2210008I11Rik; Mib2; Skd; Zzank1
UniProt ID: (Mouse) Q8R516
Entrez Gene ID: (Mouse) 76580
actin binding
ubiquitin-protein transferase activity
signal transducer activity
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
ligase activity
ribosomal S6-glutamic acid ligase activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
metal ion binding
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
ubiquitin-protein ligase
