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Invitrogen
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E3 ubiquitin-protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta-mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: E3 ubiquitin-protein ligase MIB2; EC 6.3.2.13; FLJ20648; FLJ41406; mind bomb homolog 2; RBSC-skeletrophin; RBSC-skeletrophin/dystrophin-like polypeptide
Entrez Gene ID: (Rat) 474147