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Proteintech
MIG6/ERRFI1 Polyclonal Antibody
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产品信息
11630-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
MIG6; ERRFI1 Fusion Protein Ag2202 (113-462 aa encoded by BC025337)
偶联物
形式
Liquid
浓度
0.27 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: CGFKKLTVN GVCASTPPLT PIKNSPSLFP CAPLCERGSR PLPPLPISEA LSLDDTDCEV EFLTSSDTDF LLEDSTLSDF KYDVPGRRSF RGCGQINYAY FDTPAVSAAD LSYVSDQNGG VPDPNPPPPQ THRRLRRSHS GPAGSFNKPA IRISNCCIHR ASPNSDEDKP EVPPRVPIPP RPVKPDYRRW SAEVTSSTYS DEDRPPKVPP REPLSPSNSR TPSPKSLPSY LNGVMPPTQS FAPDPKYVSS KALQRQNSEG SASKVPCILP IIENGKKVSS THYYLLPERP PYLDKYEKFF REAEETNGGA QIQPLPADCG ISSATEKPDS KTKMDLGGHV KRKHLSYVVS P (113-462 aa encoded by BC025337)
靶标信息
ERRFI1 is a cytoplasmic protein whose expression is upregulated with cell growth (Wick et al., 1995). It shares significant homology with the protein product of rat gene-33, which is induced during cell stress and mediates cell signaling (Makkinje et al., 2000).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: ERBB receptor feedback inhibitor 1; Gene 33 polypeptide; MIG-6; Mitogen-inducible gene 6 protein; Mitogen-inducible gene 6 protein homolog; RALT; Receptor-associated late transducer
基因别名: 1300002F13Rik; RALT; 33; AI788755; ERRFI1; gene 33; GENE-33; MIG-6; MIG6; Ralt; RGD1307599; Xxx
UniProt ID: (Human) Q9UJM3, (Mouse) Q99JZ7, (Rat) P05432
Entrez Gene ID: (Human) 54206, (Mouse) 74155, (Rat) 313729
negative regulation of epidermal growth factor-activated receptor activity
stress-activated protein kinase signaling cascade
negative regulation of protein autophosphorylation
negative regulation of interleukin-1 beta production
negative regulation of collagen biosynthetic process
negative regulation of epidermal growth factor receptor signaling pathway
negative regulation of tumor necrosis factor biosynthetic process
skin morphogenesis
regulation of keratinocyte differentiation
lung alveolus development
negative regulation of peptidyl-tyrosine phosphorylation
lung vasculature development
lung epithelium development
regulation of type B pancreatic cell proliferation
negative regulation of ERK1 and ERK2 cascade
negative regulation of cardiac muscle hypertrophy in response to stress
response to stress
cellular response to insulin stimulus
cellular response to platelet-derived growth factor stimulus
positive regulation of GTPase activity
cellular response to epidermal growth factor stimulus
cellular hyperosmotic response
cellular response to dexamethasone stimulus
