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Invitrogen
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PA1-21070 detects MMP-10 in human samples.
PA1-21070 has been successfully used in immunohistochemistry (paraffin) procedures.
The PA1-21070 immunogen is a synthetic peptide derived from the hinge domain of human MMP10 protein..
MMP10 belongs to the matrix metalloproteinase family, and is generally secreted in its pro form, which is further modified by extracellular proteinases. As a metalloproteinase, MMP10 requires zinc and calcium as cofactors for activity. It is involved in the activation of pro-collagenase, catabolism of collagen, degradation of fibronectin, and tissue remodeling. In humans, the gene MMP10 located on chromosome 11.
仅用于科研。不用于诊断过程。未经明确授权不得转售。