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Invitrogen
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PA1-32043 detects MMP11 from human samples.
PA1-32043 has been successfully used in immunohistochemistry, Western blot applications.
The PA1-32043 immunogen is a synthetic peptide, corresponding to amino acids 359-445 of Human MMP11.
Stromelysin, a member of the matrix metalloproteinase family, demonstrates wide substrate specificity with the ability to degrade proteoglycan, fibronectin, laminin, casein, and the nonhelical region of collagen. The stromelysin-3 (MMP-11) gene was originally identified on the basis that it is expressed specifically in stromal cells surrounding invasive breast carcinomas. MMP-11 is localized by in situ hybridization to the long arm of chromosome 22. The MMP-11 expression is found more specifically in malignant tumors than in benign ones.
仅用于科研。不用于诊断过程。未经明确授权不得转售。