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Invitrogen
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PA1-32153 detects MMP3 from human samples.
PA1-32153 has been successfully used in Western blot applications.
The PA1-32153 immunogen is: ProMMP-3 purified from cultured human rheumatoid synovial fibroblasts, shown to be homogeneous by SDS-PAGE.
MMP3 (stromelysin-1) belongs to the peptidase M10A subfamily. It is secreted in its pro-protein form, and is activated by extracellular proteinase cleavage. MMP3 is capable of binding to zinc and calcium ions, and has metallo-endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin. It is involved in normal cellular processes such as wound repair and tissue remodeling. Mutations in the gene can result in coronary heart disease 6.
仅用于科研。不用于诊断过程。未经明确授权不得转售。