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Invitrogen
MPG Polyclonal Antibody
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Product Details
PA5-79691
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminus of human MPG (228-243aa NKSFDQRDLAQDEAVW).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Liver Tissue, HELA whole cell, JURKAT whole cell.
Target Information
MPG functions in the hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine, and 7-methylguanine from the damaged DNA polymer formed by alkylation lesions.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 3' end of the Mid1 gene, localized 68 kb upstream the humanzeta globin gene on 16p; 3-alkyladenine DNA glycosylase; 3-methyladenine DNA glycosidase; 3-methyladenine DNA glycosylase; ADPG; alkylpurine-DNA-N-glycosylase; CRA36.1 (3-methyl-adenine DNA glycosylase); DNA-3-methyladenine glycosylase; N-methylpurine-DNA glycocylase; N-methylpurine-DNA glycosylase; N-methylpurine-DNA glycosylase, MPG; proliferation-inducing protein 11; proliferation-inducing protein 16
Gene Aliases: 9830006D05; AAG; ADPG; AI326268; ANPG; APNG; CRA36.1; MDG; MID1; MPG; PIG11; PIG16
UniProt ID: (Human) P29372, (Mouse) Q04841
Entrez Gene ID: (Human) 4350, (Rat) 24561, (Mouse) 268395
damaged DNA binding
alkylbase DNA N-glycosylase activity
protein binding
DNA-3-methyladenine glycosylase activity
DNA N-glycosylase activity
DNA-7-methylguanine glycosylase activity
DNA-7-methyladenine glycosylase activity
DNA-3-methylguanine glycosylase activity
DNA binding
catalytic activity
hydrolase activity
DNA metabolism protein
DNA glycosylase
nucleic acid metabolism protein
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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