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Invitrogen
MPHOSPH1 Polyclonal Antibody
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MPHOSPH1 Antibody (PA5-120351) in WB
Western blot analysis of MPHOSPH1 in extracts of various cell lines. Samples were incubated with MPHOSPH1 Polyclonal antibody (Product # PA5-120351) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10s.
产品信息
PA5-120351
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1200-1500 of human KIF20B (NP_057279.2).
偶联物
形式
Liquid
浓度
0.53 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive test controls include: U-251MG, OVCAR3, 293T, HT-29, NIH/3T3, Mouse brain, Rat brain. The target is usually found in the following locations: Cell projection, Cytoplasm, Midbody, Nucleus, axon, centrosome, cytoskeleton, growth cone, microtubule organizing center, nucleolus, nucleoplasm, spindle, spindle pole.
Immunogen sequence: KHLLQLKEEE EETNRQETEK LKEELSASSA RTQNLKADLQ RKEEDYADLK EKLTDAKKQI KQVQKEVSVM RDEDKLLRIK INELEKKKNQ CSQELDMKQR TIQQLKEQLN NQKVEEAIQQ YERACKDLNV KEKIIEDMRM TLEEQEQTQV EQDQVLEAKL EEVERLATEL EKWKEKCNDL ETKNNQRSNK EHENNTDVLG KLTNLQDELQ ESEQKYNADR KKWLEEKMML ITQAKEAENI RNKEMKKYAE DRERFFKQQN EMEILTAQLT EKDSDLQKWR EERDQLVAAL EIQLKALISS N
靶标信息
KIF20B is a plus-end-directed motor enzyme that is required for completion of cytokinesis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cancer/testis antigen 90; CT90; Kinesin family member 20B; Kinesin-like protein KIF20B; Kinesin-related motor interacting with PIN1; M-phase phosphoprotein 1; mitotic kinesin-like protein; mitotic kinesin-related protein; MPP1; N-6 kinesin
基因别名: 33cex; B130024C23; C330014J10Rik; CT90; KIF20B; KRMP1; magoo; MPHOSPH1; MPP-1; MPP1
UniProt ID: (Human) Q96Q89, (Mouse) Q80WE4
Entrez Gene ID: (Human) 9585, (Mouse) 240641, (Rat) 309523
neural tube closure
microtubule-based movement
cell cycle arrest
mitotic nuclear division
regulation of mitotic nuclear division
positive regulation of cell proliferation
positive regulation of cytokinesis
protein localization to microtubule
neuron projection morphogenesis
cell division
positive regulation of intracellular protein transport
positive regulation of mitotic cytokinetic process
regulation of establishment of cell polarity
positive regulation of neuron migration
cell cycle
metabolic process
regulation of establishment of protein localization
regulation of neuron migration
