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Proteintech
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Sequence of this protein is as follows: MLQTSNGATP ALLGEVENSV VLSCMEEAKQ LVDRAYKERR ESIKRSLQSG SASPTELLFY FKQPVAGTRT AVRAADYLHV ALDLLKRKLQ PLWPRPFNVT DVLTPAQLNL LSVSSGCAYQ DVGVTCPPND KYRTITGHCN NRRSPTLGAS NRAFVRWLPA EYEDGVSMPF GWTPGVNRNG FKVPLARQVS NAIVRFPNDQ LTKDQERALM FMQWGQFLDH DITLTPEPAT RFSFFTGLNC ETSCLQQPPC FPLKIPPNDP RIKNQKDCIP FFRSCPACTR NNITIRNQIN ALTSFVDASG VYGSEDPLAR KLRNLTNQLG LLAVNTRFQD NGRALMPFDS LHDDPCLLTN RSARIPCFLA GDMRSSEMPE LTSMHTLFVR EHNRLATQLK RLNPRWNGEK LYQEARKIVG AMVQIITYRD YLPLVLGPAA MKKYLPQYRS YNDSVDPRIA NVFTNAFRYG HTLIQPFMFR LNNQYRPTGP NPRVPLSKVF FASWRVVLEG GIDPILRGLM ATPAKLNRQN QIVVDEIRER LFEQVMRIGL DLPALNMQRS RDHGLPGYNA WRRFCGLPQP STVGELGTVL KNLELARKLM AQYGTPNNID IWMGGVSEPL EPNGRVGQLL ACLIGTQFRK LRDGDRFWWE NPGVFSKQQR QALASISLPR IICDNTGITT VSKNNIFMSN TYPRDFVSCN TLPKLNLTSW KET
Myeloperoxidase (MPO) is a heme protein that is synthesized during myeloid differentiation and is a major component of neutrophil azurophilic granules. It is produced as a single chain precursor and subsequently cleaved into a light and heavy chain. The mature MPO is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme is responsible for producing hypohalous acids that are central to the microbicidal activity of neutrophils. Diseases that are associated with MPO include Myeloperoxidase Deficiency and Alzheimer's Disease, Familial, 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: preproprotein; unnamed protein product
基因别名: mKIAA4033
UniProt ID: (Mouse) P11247
Entrez Gene ID: (Mouse) 17523, (Rat) 303413