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Proteintech
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The antibody recognizes the C-term of isoform 2 and isoform 3 of MPRIP.
Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: p116 Rho interacting protein; Rho interacting protein 3; rho-interacting protein 3; Rho-interacting protein 3 (p116RIP) (RIP3); RIP3; unnamed protein product
基因别名: 9530046C02; Gm34094; M-RIP; mKIAA0864; MRIP; p116Rip; RHOIP3; RIP3
UniProt ID: (Human) Q6WCQ1, (Rat) Q9ERE6, (Mouse) P97434
Entrez Gene ID: (Human) 23164, (Rat) 116504, (Mouse) 26936