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Invitrogen
MRG15 Polyclonal Antibody
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MRG15 Antibody (PA5-78349) in ICC/IF
MRG15 Polyclonal Antibody detects MRG15 protein at nucleus by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: MRG15 protein stained by MRG15 Polyclonal Antibody (Product # PA5-78349) diluted at 1:1,000. Blue: Hoechst 33342 staining.
产品信息
PA5-78349
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human MRG15. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1.00 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Control: Huh7, Hep3B, mouse liver
Predicted Reactivity: Rat (100%), Zebrafish (91%), Xenopus laevis (92%), Rabbit (100%), Chicken (98%), Rhesus Monkey (100%), Bovine (99%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Esa1p-associated factor 3 homolog; MGC10631; MORF-related gene 15 protein; MORF-related gene on chromosome 15; Mortality factor 4-like protein 1; MRG15; Protein MSL3-1; testis expressed gene 189; Testis-expressed gene 189 protein; Transcription factor-like protein MRG15
基因别名: Eaf3; FWP006; HSPC008; HSPC061; HsT17725; MEAF3; mKIAA4002; MORF4L1; MORFRG15; MRG15; PP368; S863-6; TEG-189; Tex189
UniProt ID: (Human) Q9UBU8, (Mouse) P60762
Entrez Gene ID: (Human) 10933, (Mouse) 21761
double-strand break repair via homologous recombination
chromatin remodeling
chromatin silencing
transcription, DNA-templated
cell proliferation
chromatin modification
histone deacetylation
regulation of growth
histone H4 acetylation
histone H2A acetylation
DNA repair
DNA recombination
regulation of transcription, DNA-templated
cellular response to DNA damage stimulus
