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NeoBiotechnologies
MRP3 (Multidrug Resistance-Associated Protein 3) Monoclonal Antibody (ABCC3, 2971)
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MRP3 (Multidrug Resistance-Associated Protein 3) Antibody (8714-MSM1-P1ABX) in IHC (P)
Immunohistochemistry (Paraffin) analysis performed in formalin fixed, paraffin-embedded human pancreatic carcinoma using MRP3 (Multidrug Resistance-Associated Protein 3) Monoclonal Antibody (Product # 8714-MSM1-P1ABX).
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
8714-MSM1-P1ABX
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
ABCC3, 2971
抗原
Recombinant fragment (around aa 815-957) of human MRP3 (ABCC3) protein
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A/G
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Immunohistochemistry (PFA fixed): incubate antibody for 30 min RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 degrees C followed by cooling at RT for 20 minutes.
靶标信息
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ATP-binding cassette, sub-family C (CFTR/MRP), member 3; canalicular multispecific organic anion transporter 2; canicular multispecific organic anion transporter; cMOAT2/MRP3; DKFZp686E22157; homolog of the multidrug resistance-associated protein MRP1; MRP transporter family; MRP/cMOAT-related ABC transporter; multi-specific organic anion transporter D; multidrug resistance associated protein; multidrug resistance-associated protein 3; similar to multidrug resistance protein MRP3
基因别名: ABC31; cMOAT2; EST90757; MLP2; MOAT-D; MRP3
UniProt ID: (Human) O15438
Entrez Gene ID: (Human) 8714
ATP binding
xenobiotic-transporting ATPase activity
glucuronoside transmembrane transporter activity
glutathione S-conjugate-exporting ATPase activity
bile acid-exporting ATPase activity
ATPase activity
transmembrane transporter activity
ATPase activity, coupled to transmembrane movement of substances
xenobiotic transporter activity
icosanoid transmembrane transporter activity
ABC-type transporter activity
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