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Invitrogen
MVK Polyclonal Antibody
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MVK Antibody (PA5-92415) in WB
Western blot analysis of MVK in extracts of various cell lines. Samples were incubated with MVK Polyclonal antibody (Product # PA5-92415) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 60s.
产品信息
PA5-92415
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human MVK (NP_0004221)
偶联物
形式
Liquid
浓度
0.72 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: RLQPHSNGKV DLSLPNIGIK RAWDVARLQS LDTSFLEQGD VTTPTSEQVE KLKEVAGLPD DCAVTERLAV LAFLYLYLSI CRKQRALPSL DIVVWSELPP GAGLGSSAAY SVCLAAALLT VCEEIPNPLK DGDCVNRWTK EDLELINKWA FQGERMIHGN PSGVDNAVST WGGALRYHQG KISSLKRSPA LQILLTNTKV PRNTRALVAG VRNRLLKFPE IVAPLLTSID AISLECERVL GEMGEAPAPE QYLVLEELID M; Positive Samples: Raji, BT-474; Cellular Location: Cytoplasm
靶标信息
Mevalonate kinase (MVK) is an early enzyme in isoprenoid and sterol synthesis. Mevalonate kinase catalyzes the ATP-dependent phosphorylation of mevalonic acid to form mevalonate 5-phosphate. Deficiency in MVK activity contributes to mevalonic aciduria and hyperimmunoglobulinemia D/periodic fever syndrome (HIDS).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: KIME; LH receptor mRNA-binding protein; Mevalonate kinase; mevalonate kinase 1; MK
基因别名: LRBP; MK; MVK; MVLK; POROK3
UniProt ID: (Human) Q03426
Entrez Gene ID: (Human) 4598
