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Proteintech
MYBPC3 Monoclonal Antibody (3C8F8), CoraLite® 594
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产品信息
CL594-67608
产品规格
种属反应
Human,
Mouse,
Pig,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
3C8F8
抗原
MYBPC3 fusion protein Ag15848
偶联物
激发/发射光谱
593/614 nm
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol, 0.5% BSA
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: MPEPGKKPV SAFSKKPRSV EVAAGSPAVF EAETERAGVK VRWQRGGSDI SASNKYGLAT EGTRHTLTVR EVGPADQGSY AVIAGSSKVK FDLKVIEAEK AEPMLAPAPA PAEATGAPGE APAPAAELGE SAPSPKGSSS AALNGPTPGA PDDPIGLFVM RPQDGEVTVG GSITFSARVA GASLLKPPVV KWFKGKWVDL SSKVGQHLQL HDSYDRASKV YLFELHITDA QPAFTGSYRC EVSTKDKFDC SNFNLTVHEA MGTGDLDLLS AFRRTSLAGG GRRISDSHED TGILDFSSLL KKRDSFRTPR DSKLEAPAEE DVWEILRQA
靶标信息
Myosin binding protein C, cardiac-type (MYBPC3) is a thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments. It modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. Mutations affecting the gene can result in cardiomyopathy - familial hypertrophic 4, cardiomyopathy - dilated 1MM, or left ventricular non-compaction 10.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-protein, cardiac muscle isoform; cardiac C-protein; Cardiac MyBP-C; DKFZp779E1762; myosin binding protein C, cardiac; Myosin-binding protein C, cardiac-type; truncated cardiac myosin-binding protein C
基因别名: CMD1MM; CMH4; FHC; LVNC10; MYBP-C; MYBPC3
UniProt ID: (Human) Q14896, (Rat) P56741
Entrez Gene ID: (Pig) 100628050, (Human) 4607, (Rat) 295929, (Mouse) 17868
regulation of heart rate
heart morphogenesis
muscle contraction
regulation of striated muscle contraction
cell adhesion
regulation of heart contraction
myosin filament assembly
sarcomere organization
ventricular cardiac muscle tissue morphogenesis
cardiac muscle contraction
muscle filament sliding
positive regulation of ATPase activity
regulation of muscle filament sliding
