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Invitrogen
MYF5 Polyclonal Antibody
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产品信息
PA5-75281
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to amino acids 60-100 of Human MYF5.
偶联物
形式
Liquid
浓度
1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
Myogenic factor 5 (MYF5) is a gene located on chromosome 12q21.31, encoding a basic helix-loop-helix (bHLH) transcription factor essential for skeletal muscle development and differentiation. MYF5 is one of the key members of the myogenic regulatory factor (MRF) family, which also includes MyoD, myogenin, and MRF4. It plays a crucial role in myogenesis by regulating the expression of genes necessary for muscle precursor cell proliferation and differentiation into mature muscle fibers. During embryonic development, MYF5 is involved in the formation of muscle tissue and maintenance of muscle progenitor cells. Mutations or dysregulation in MYF5 can lead to developmental abnormalities in muscle formation and are implicated in muscle-related disorders. Research into MYF5 continues to explore its regulatory mechanisms in muscle biology and potential therapeutic applications in muscular dystrophies and muscle repair processes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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