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Invitrogen
MYO9B Polyclonal Antibody
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产品信息
PA5-59838
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.6 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: TDGERSAKKP AVQKKKPGDA SSLPDAGLSP GSQVDSKSTF KRLFLHKTKD KKYSLEGAEE LENAVSGHVV LEATTM
Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 62%.
靶标信息
This gene encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: celiac disease 4; myosin; myosin-IXb; unconventional myosin IXb; Unconventional myosin-9b; Unconventional myosin-IXb
基因别名: CELIAC4; MYO9B; MYR5
UniProt ID: (Human) Q13459
Entrez Gene ID: (Human) 4650
microfilament motor activity
actin binding
GTPase activator activity
protein binding
calmodulin binding
ATP binding
zinc ion binding
ATPase activity
Rho GTPase binding
actin-dependent ATPase activity
protein homodimerization activity
ATP-dependent protein binding
ADP binding
Roundabout binding
actin filament binding
