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Invitrogen
MYSM1 Polyclonal Antibody
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产品信息
PA5-62947
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human MYSM1
偶联物
形式
Liquid
浓度
0.3 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: KQDETLSSSE ITLWTEKQSN GDKKSIELND QKFNELIKNC NKHDGRGIIV DARQLPSPEP CEIQKNLNDN EMLFHSCQMV EESHEEEELK
Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 44%.
靶标信息
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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