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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Positive Control: HeLa, HepG2
Predicted Reactivity: Mouse (86%), Chicken (81%), Bovine (88%)
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Metalloprotease that specifically deubiquitinates monoubiquitinated histone H2A, a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Preferentially deubiquitinates monoubiquitinated H2A in hyperacetylated nucleosomes. Deubiquitination of histone H2A leads to facilitate the phosphorylation and dissociation of histone H1 from the nucleosome. Acts as a coactivator by participating in the initiation and elongation steps of androgen receptor (AR)-induced gene activation.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: histone H2A deubiquitinase MYSM1; myb-like, SWIRM and MPN domain-containing protein 1; RP4-592A1.1; unnamed protein product
基因别名: 2A-DUB; 2ADUB; BMFS4
UniProt ID: (Human) Q5VVJ2
Entrez Gene ID: (Human) 114803