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Mannose-binding protein C Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
BS-1582R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human Mannose-binding protein C, amino acids 31-130.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
MBL2 is a calcium-dependent lectin involved in innate immune defense. It binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. It also binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 may bind DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activates complement system; collectin-1; Collectin1; liver regeneration-related protein LRRG037; liver regeneration-related protein LRRG053; mannan-binding lectin; mannan-binding protein; mannose binding lectin 2 (protein C); mannose binding lectin, liver (C); mannose-binding lectin (protein C) 2; mannose-binding lectin (protein C) 2, soluble (opsonic defect); mannose-binding lectin 2, soluble (opsonic defect); mannose-binding protein C (liver); mannose-binding protein C precursor; mannose-binding protein C-like; MBP-C; MBPC; MGC116832; MGC116833; RA-reactive factor P28A subunit; ra-reactive factor polysaccharide-binding component p28A; raRF p28A; RARF/P28A; unnamed protein product
基因别名: Ab2-001; Ab2-011; COLEC1; HSMBPC; L-MBP; MBL; MBL-C; MBL2D; MBP; MBP-C; MBP1; MBPD; RARF/P28A
UniProt ID: (Human) P11226, (Mouse) P41317, (Rat) P08661
Entrez Gene ID: (Human) 4153, (Mouse) 17195, (Rat) 64668
complement activation, lectin pathway
activation of membrane attack complex
cell surface pattern recognition receptor signaling pathway
proteolysis
complement activation
opsonization
positive regulation of protein processing
zymogen activation
killing of cells of other organism
surfactant homeostasis
innate immune response
positive regulation of complement activation
negative regulation of viral process
positive regulation of phagocytosis
defense response to Gram-positive bacterium
protein maturation
antibacterial innate immune response
antiviral innate immune response
positive regulation of opsonization
acute-phase response
response to oxidative stress
defense response to bacterium
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