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Invitrogen
Matrine Recombinant Mouse Monoclonal Antibody (1D6)
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Matrine Antibody (MA566428) in SDS-PAGE
SDS-PAGE characterization of Matrine under reducing conditions. Lane M: Protein marker (kDa); Lane MAT: Purified Matrine Recombinant Monoclonal (Product # MA566428). Matrine showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-301.
产品信息
MA566428
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1D6
抗原
Conjugate of MAT hapten and KLH.
偶联物
形式
Liquid
浓度
6.8 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Matrine is an alkaloid derived from the plant Sophora flavescens, commonly known as Ku Shen, and is recognized for its diverse biological activities, including anticancer, antimicrobial, antibacterial, and anti-pest properties. The compound has been extensively studied for its pharmaceutical applications due to its ability to induce endoplasmic reticulum stress and activate apoptosis, making it a promising candidate for anticancer therapies. Despite its potential, matrine's low bioavailability, poor chemical stability, and central nervous system toxicity have prompted researchers to develop matrine derivatives with enhanced biological activity and safety profiles. These derivatives are synthesized through modifications that improve their chemical stability and biological efficacy, as evidenced by various in vitro and in vivo evaluations. The structural characterization of these derivatives is typically performed using techniques such as 1H NMR, 13C NMR, and ESI-MS spectral analyses.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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