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QED Bioscience
Measles Nucleoprotein Monoclonal Antibody (2F3)
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产品信息
90018-100UG
产品规格
种属反应
Virus
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
2F3
抗原
Recombinant Measles virus nucleoprotein.
偶联物
形式
Lyophilized
浓度
0.5-1.0 mg/mL
纯化类型
Protein A
保存液
0.1M tris with 0.1M glycine, 2% sucrose
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitute in distilled water.
靶标信息
Encapsidates the genome in a ratio of 1 N per 6 ribonucleotides, protecting it from nucleases. The nucleocapsid (NC) has a helical structure with either 12.35 or 11.64 N per turn, approximately 20 nm in diameter, with a hollow central cavity approximately 5 nm in diameter. The encapsidated genomic RNA is termed the NC and serves as template for transcription and replication. During replication, encapsidation by N is coupled to RNA synthesis and all replicative products are resistant to nucleases. N is released in the blood following lysis of measles infected cells, it interacts then with human FCGR2B on immune cells, inducing apoptosis and blocking inflammatory immune response. Ntail binds to a protein on human thymic epithelial cells, termed Nucleoprotein Receptor (NR), inducing growth arrest.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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