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Bioss
Musashi 1/2 Polyclonal Antibody
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产品信息
BS-11201R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human Musashi 1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Musashi1 (Msi1) is an RNA-binding protein expressed in neural progenitor cells and neural stem cells. Msi1 is the mammalian homolog of Drosophila Musashi. The gene encoding human Msi1 encodes a 362 amino acid protein. In murine embryonic neural progenitor cells, Msi1 localizes to the cytoplasm and is downregulated during differentiation. Msi1 binds to NUMB, which encodes a membrane-associated antagonist of Notch signaling. Msi1 appears to function in the proliferation and maintenance of stem cell populations of the central nervous system. In addition to its usefulness as a marker for neural progenitor cells in normal human brains, Msi1 is also a marker for human gliomas. In rats, Msi1 is expressed in Sertoli cells of the testis and granulosa cells of the ovary.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Musashi homolog 1(Drosophila); Musashi homolog 2; musashi RNA-binding protein 1; musashi RNA-binding protein 2; Musashi-1; Musashi-2; musashi1; Musashi2; RNA-binding protein Musashi homolog 1; RNA-binding protein Musashi homolog 2
基因别名: 1700105C15Rik; AI451722; AI563628; AW489193; m-Msi-1; MSI1; Msi1h; MSI2; MSI2H; Musahi1; RGD1560397
UniProt ID: (Human) O43347, (Human) Q96DH6, (Mouse) Q61474, (Rat) Q8K3P4, (Mouse) Q920Q6
Entrez Gene ID: (Human) 4440, (Human) 124540, (Mouse) 17690, (Rat) 259272, (Mouse) 76626, (Rat) 360596
