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Invitrogen
Myosin Skeletal/Smooth Muscle Polyclonal Antibody
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产品信息
PA1-28038
产品规格
种属反应
Bovine,
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Whole myosin (heavy and light chains) from bovine uterus.
偶联物
形式
Liquid
浓度
Conc. Not Determined
保存液
whole serum
内含物
15mM sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Myosin proteins are motor proteins critical for muscle contraction in both skeletal and smooth muscle. They convert chemical energy from ATP hydrolysis into mechanical energy, generating force and movement along actin filaments. In skeletal muscle, myosin molecules are part of the contractile apparatus, where they form thick filaments that interact with actin thin filaments to produce contraction. Myosin heavy chain (MyHC) isoforms are key determinants of muscle fiber types, contributing to the diversity in muscle function and specialization. Skeletal muscle fibers can express different MyHC isoforms, resulting in fibers with varying speed and endurance characteristics. Smooth muscle myosin, in contrast, is involved in the involuntary contractions of smooth muscle tissues found in the walls of hollow organs, such as the intestines and blood vessels. Smooth muscle myosin's regulatory mechanisms differ significantly from skeletal muscle, involving phosphorylation of the myosin light chain to initiate contraction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: contractile protein; epididymis luminal protein 71; MyHC-2x; MyHC-IIx/d; Myosin heavy chain 1; Myosin heavy chain 11; Myosin heavy chain 2x; Myosin heavy chain IIx/d; myosin heavy chain SMA; Myosin heavy chain, skeletal muscle, adult 1; Myosin heavy chain, smooth muscle isoform; myosin, heavy chain 1, skeletal muscle, adult; myosin, heavy chain 11, smooth muscle; myosin, heavy polypeptide 1, skeletal muscle, adult; myosin, heavy polypeptide 11, smooth muscle; Myosin-1; Myosin-11; SMMHC; type 2x myosin heavy chain
基因别名: AAT4; FAA4; HEL71; KIAA0866; MYH1; MYH11; MYHa; MyHC-2x; MyHC-2X/D; MYHSA1; SMHC; SMMHC
UniProt ID: (Human) P12882, (Bovine) Q9BE40, (Human) P35749
Entrez Gene ID: (Human) 4619, (Bovine) 281337, (Bovine) 530050, (Human) 4629
