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Invitrogen
N2DL4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-114505
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RAET1E antibody was raised against an 18 amino acid peptide near the center of human RAET1E. The immunogen is located within amino acids 160 - 210 of RAET1E.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive controls that may be used include: EL4 Cell Lysate, K-562 Cell Slide
靶标信息
This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: GPI-anchored membrane glycoprotein; REA-1 epsilon; Rae-1e; ligand for NKG2D receptor; lymphocyte effector toxicity activation ligand; MGC125309; NKG2D ligand 4; NKG2D-ligand; RAE-1 epsilon; RAE-1-like transcript 4; RAE1 like transcript 4; RL-4; membrane glycoprotein; stress-inducible antigen; UL16 binding protein 4; UL16-binding protein 4; ULBP 4; ULBP4MGC125308; unnamed protein product
基因别名: bA350J20.7; LETAL; N2DL-4; NKG2DL4; RAET1E2; RL-4; ULBP4
UniProt ID: (Human) Q8TD07, (Mouse) Q9CZQ6
Entrez Gene ID: (Human) 135250, (Mouse) 379043
positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of endogenous peptide antigen via MHC class Ib
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent
signal transduction
natural killer cell mediated cytotoxicity
positive regulation of natural killer cell mediated cytotoxicity
T cell mediated cytotoxicity
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
