Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
NADK Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
图: 1 / 1
NADK Antibody (PA5-97993) in WB
Western Blot analysis of NADK using a NADK Polyclonal antibody (Product # PA5-97993) at a concentration of 1.7 µg/mL. Positive WB detected in: SH-SY5Y whole cell lysate. A secondary Goat polyclonal antibody to rabbit IgG was applied at a 1:50,000 dilution. Observed band size: 47 kDa.
产品信息
PA5-97993
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human NAD kinase protein (1-300AA)
偶联物
形式
Liquid
浓度
5 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
NADK (Nicotinamide Adenine Dinucleotide Kinase) is an enzyme crucial in the regulation of intracellular NADP+ levels, which are necessary for metabolic processes such as fatty acid and DNA synthesis. The human NADK gene is located on chromosome 1p36.33 and encodes a protein that primarily functions in the cytoplasm. NADK catalyzes the phosphorylation of NAD+ to NADP+, playing a significant role in maintaining the cellular redox state. Structurally, human NADK forms a dimeric organization, as revealed by its crystal structure, and includes four subunits (chains A-D) with specific colors indicating different chains. The enzyme's activity is regulated post-translationally, but its pathophysiological significance in humans remains underexplored. Multiple orthologs of the NADK gene are present in various organisms, illustrating its evolutionary conservation and importance across different species.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: FLJ13052; NAD kinase; Poly(P)/ATP NAD kinase; ppnk
基因别名: dJ283E3.1; NADK
UniProt ID: (Human) O95544
Entrez Gene ID: (Human) 65220
