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Invitrogen
NAPRT1 Polyclonal Antibody
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NAPRT1 Antibody (PA5-88160) in WB
Western blot analysis of NAPRT1 in extracts of various cell lines. Samples were incubated with NAPRT1 Polyclonal antibody (Product # PA5-88160) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-88160
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 309-538 of human NAPRT1 (NP_6602023)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.73 mg/mL
规格
73 µg
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: ELGYRAVGVR LDSGDLLQQA QEIRKVFRAA AAQFQVPWLE SVLIVVSNNI DEEALARLAQ EGSEVNVIGI GTSVVTCPQQ PSLGGVYKLV AVGGQPRMKL TEDPEKQTLP GSKAAFRLLG SDGSPLMDML QLAEEPVPQA GQELRVWPPG AQEPCTVRPA QVEPLLRLCL QQGQLCEPLP SLAESRALAQ LSLSRLSPEH RRLRSPAQYQ VVLSERLQAL VNSLCAGQSP; Positive Samples: HepG2, HT-29; Cellular Location: Cytoplasm, cytosol
靶标信息
Nicotinic acid (NA; niacin) is converted by nicotinic acid phosphoribosyltransferase (NAPRT; EC 2.4.2.11) to NA mononucleotide (NaMN), which is then converted to NA adenine dinucleotide (NaAD), and finally to nicotinamide adenine dinucleotide (NAD), which serves as a coenzyme in cellular redox reactions and is an essential component of a variety of processes in cellular metabolism including response to stress (Hara et al., 2007).
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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