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Proteintech
NEIL1 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
12145-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NEIL1 Fusion Protein Ag2793 (1-390 aa encoded by BC010876)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.13 mg/mL
规格
19.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MPEGPELHL ASQFVNEACR ALVFGGCVEK SSVSRNPEVP FESSAYRISA SARGKELRLI LSPLPGAQPQ QEPLALVFRF GMSGSFQLVP REELPRHAHL RFYTAPPGPR LALCFVDIRR FGRWDLGGKW QPGRGPCVLQ EYQQFRENVL RNLADKAFDR PICEALLDQR FFNGIGNYLR AEILYRLKIP PFEKARSVLE ALQQHRPSPE LTLSQKIRTK LQNPDLLELC HSVPKEVVQL GGRGYGSESG EEDFAAFRAW LRCYGMPGMS SLQDRHGRTI WFQGDPGPLA PKGRKSRKKK SKATQLSPED RVEDALPPSK APSRTRRAKR DLPKRTATQR PEGTSLQQDP EAPTVPKKGR RKGRQAASGH CRPRKVKADI PSLEPEGTSA S (1-390 aa encoded by BC010876)
靶标信息
NEIL1 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: DNA endonuclease eight-like glycosylase 1; DNA glycosylase/AP lyase Neil1; DNA-(apurinic or apyrimidinic site) lyase Neil1; endonuclease VIII; endonuclease VIII-like 1; FLJ22402; NEH1; nei endonuclease VIII-like 1; nei homolog 1; nei-like protein 1; unnamed protein product
基因别名: 2810450N13Rik; FPG1; hFPG1; NEH1; NEI1
UniProt ID: (Human) Q96FI4, (Mouse) Q8K4Q6
Entrez Gene ID: (Human) 79661, (Rat) 367090, (Mouse) 72774
nucleic acid binding
damaged DNA binding
DNA-(apurinic or apyrimidinic site) lyase activity
protein binding
zinc ion binding
hydrolase activity, acting on glycosyl bonds
hydrolase activity, hydrolyzing N-glycosyl compounds
lyase activity
DNA N-glycosylase activity
class I DNA-(apurinic or apyrimidinic site) endonuclease activity
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