Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Proteintech
NELFB Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
产品信息
16418-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
NELFB Fusion Protein Ag9599 (127-475 aa encoded by BC011892)
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
The MW of this protein is 66 kDa, and this antibody specifically recognizes the 66 kDa protein.
Immunogen sequence: VHYCTLRAE LLMSLHDLDV GEICTVDPCH KFTWCLDACI RERFVDSKRA RELQGFLDGV KKGQEQVLGD LSMILCDPFA INTLALSTVR HLQELVGQET LPRDSPDLLL LLRLLALGQG AWDMIDSQVF KEPKMEVELI TRFLPMLMSF LVDDYTFNVD QKLPAEEKAP VSYPNTLPES FTKFLQEQRM ACEVGLYYVL HITKQRNKNA LLRLLPGLVE TFGDLAFGDI FLHLLTGNLA LLADEFALED FCSSLFDGFF LTASPRKENV HRHALRLLIH LHPRVAPSKL EALQKALEPT GQSGEAVKEL YSQLGEKLEQ LDHRKPSPAQ AAETPALELP LPSVPAPAPL (127-475 aa encoded by BC011892)
靶标信息
NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2), either NELFC or NELFD (TH1L), and NELFE (RDBP), a heterodimer of SPT4 (SUPT4H1), to cause transcriptional pausing of RNA polymerase II (Narita et al., 2003).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Cofactor of BRCA1; DKFZp586B0519; Negative elongation factor B; negative elongation factor complex member B, Cobra1; negative elongation factor protein B; NELF-B; ortholog of human cofactor of BRCA1 (COBRA1); RP13-122B23.3
基因别名: A730008L03Rik; AB041607; AI663983; COBRA1; KIAA1182; MNCb-5210; NELF-B; NELFB; RGD1307832
UniProt ID: (Human) Q8WX92, (Mouse) Q8C4Y3
Entrez Gene ID: (Human) 25920, (Mouse) 58202, (Rat) 311796
transcription, DNA-templated
regulation of transcription, DNA-templated
negative regulation of transcription, DNA-templated
translational elongation
biological_process
transcription from RNA polymerase II promoter
transcription elongation from RNA polymerase II promoter
negative regulation of transcription elongation from RNA polymerase II promoter
positive regulation of viral transcription
