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Invitrogen
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PA1-32116 contains 50 ug of free control peptide MES CYN PGL DGI IEY DDF K.
PA1-32116 detects NFkB p52 from human samples.
PA1-32116 has been successfully used in immunoprecipitation, Western blot and ELISA applications.
The PA1-32116 immunogen is Human NFkB p52/p100 peptide corresponding to a region near the N-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH).
Store at 4°C short term. For extended storage, store at -20°C, avoiding freeze/thaw cycles.
The NFkB transcription factor was originally identified as a protein complex consisting of a DNA binding subunit and an associated protein. The subunit is functionally related to c-Rel p75 and Rel B p68. The p50 subunit was initially believed to be a functionally unique protein derived from the amino-terminus of a precursor designated p105. A cDNA has been isolated that encodes an alternative DNA binding subunit of NFkB. It is synthesized as a protein that is expressed in a variety of cell types and, like p105, undergoes cleavage to generate its NFkB subunit, in this case a protein designated p52 (previously referred to as p49). In contrast to p50 derived from p105, p52 acts in synergy with p65 to stimulate the HIV enhancer in transiently transfected Jurkat cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。