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Invitrogen
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Immunogen sequence: FKDLDISCAS LPHMHKNPPP SPAPEPTVIR LEDKNVLVDN IELASTSSPE EKPKVFIIHS
Highest antigen sequence identity to the following orthologs: Mouse - 78%, Rat - 82%.
NIPAL4 acts as a Mg(2+) transporter and can also transport other divalent cations such as Ba(2+), Mn(2+), Sr(2+) and Co(2+) but to a much less extent than Mg(2+). NIPAL4 may also be a receptor for ligands (trioxilins A3 and B3) from the hepoxilin pathway. The NIPAL4 gene likely encodes a membrane receptor. Mutations in the NIPAL4 gene have been associated with autosomal recessive congenital ichthyosis. Diseases associated with NIPAL4 include Ichthyosis, Congenital, Autosomal Recessive 6 and Autosomal Recessive Congenital Ichthyosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ichthyin; Magnesium transporter NIPA4; NIPA-like domain containing 4; NIPA-like protein 4; Non-imprinted in Prader-Willi/Angelman syndrome region protein 4
基因别名: ARCI6; ICHN; ICHTHYIN; ICHYN; NIPA4; NIPAL4
UniProt ID: (Human) Q0D2K0
Entrez Gene ID: (Human) 348938